Novembala 30, 2023

Kupita patsogolo kwa katemera wa mRNA kumapangitsa thanzi la anthu

Kodi katemera wa mRNA ndi chiyani?

katemera wa mRNA, kapena messenger ribonucleic acid katemera, kuimira gulu latsopano la katemera. Amagwiritsa ntchito gawo lopangira ma genetic kuchokera ku tizilombo toyambitsa matenda kuti tiyambitse Poyankha m'thupi. Kuphatikiza apo, gawo ili la mRNA limakhazikika information kwa gawo la tizilombo toyambitsa matenda, nthawi zambiri puloteni kapena chidutswa cha mapuloteni. Chifukwa chake, chitetezo chamthupi chimazindikira ndikuyankha.

Poyambitsa mRNA m'thupi amalangiza maselo kuti apange mapuloteni a tizilombo toyambitsa matenda kwakanthawi. Kuphatikiza apo, izi zimayendetsa chitetezo chamthupi, kupanga ma antibodies ndi ma cell a chitetezo chamthupi. Amatha kuzindikira ndikuchotsa tizilombo toyambitsa matenda ngati matenda amtsogolo achitika. Katemera wa mRNA alibe ma virus amoyo ndipo sangayambitse matenda. Komanso, amagwira ntchito ngati a wamphamvu, chida chosinthika popewa matenda opatsirana, monga momwe zasonyezedwera ndi COVID-19.

Udindo wa Bioreactor pakupanga katemera wa mRNA

Kupanga katemera wa mRNA kwadziwika kwambiri Chofunikira kwambiri mu biotechnology. Zowonadi, ma bioreactors ndi ofunikira pakuchita izi. Amalola kukhathamiritsa kwa chikhalidwe cha ma cell ndikuwongolera bwino momwe zinthu ziliri. Izi zimatsimikizira ubwino ndi mphamvu zofunikira popanga katemera wotetezeka. Zotsatira zake, ukadaulo wa bioreactor udakali wofunikira pakuwongolera mavuto azaumoyo wa anthu padziko lonse lapansi.

Komanso, machitidwe athu a bioreactor ndi TFF ⇀ kupereka yankho lathunthu. Komanso, amawonetsetsa kusintha kosavuta kuchokera ku kafukufuku kupita kukupanga msika. Izi zikuphatikiza kudzipereka kwathu pakupanga zatsopano zasayansi.

Mavuto ndi mayendedwe amtsogolo

Ngakhale pali zovuta zomwe zikupitilira monga kukhathamiritsa kwa kupanga ndi kuwongolera mlingo, tsogolo likuwoneka bwino. Mwachitsanzo, matekinoloje oyambira ma virus, ma VLPs, ndi ma AAV akukonzekera njira yatsopano yamankhwala. Ankatha kulola kupewa matenda, kuwachiritsa, ngakhale kuwathetsa.

Kuphatikiza apo, chithandizo cha gulu la asayansi ndi kupita patsogolo kwaukadaulo ndikofunikira. Chifukwa chake, njira zatsopanozi zitha kupititsa patsogolo thanzi lapadziko lonse lapansi ndikuthana ndi matenda oopsa.

Kuyankha kwa mliri ndi kupitirira

The Covid 19 mliri wawunikira ntchito yofunika kwambiri ya biotechnology, makamaka ma bioreactors pakupanga katemera ndi kupanga. Machitidwe apamwambawa ndi ofunikira kukulitsa kupanga pamene kusunga khalidwe ndi bwino. Pamene makampaniwa akukula, ukadaulo wa bioreactor umagwirizana ndi zosowa zomwe zikubwera, ndikuwonetsetsa kupezeka kwa chithandizo chofunikira chodzitetezera ku thanzi la anthu padziko lonse lapansi.

Zatsopano mu kapangidwe ka bioreactor

Biotechnology ikupita patsogolo mwachangu ndi mapangidwe apamwamba a bioreactor. Makamaka, kugwiritsa ntchito ma cell a mammalian ikukula kwambiri, ikufuna zida zomwe zimatha kuthana ndi zikhalidwe zama cell zovuta. Kutsogola kwaukadaulo wa bioreactor kumathandizira kupanga izi. Chifukwa chake, zimapangitsa kuti pakhale kuwongolera komanso kuwongolera kwabwino mu biotherapeutics ndi kupanga katemera. Kuphatikiza apo, izi zimakulitsa mwayi wamankhwala okhazikika komanso osinthika, opereka chiyembekezo chatsopano komanso chithandizo chamankhwala osiyanasiyana.

Zotsatira ndi tsogolo la bioreactors paumoyo wa anthu

TECNICMa bioreactors amatha kutengera zosowa zenizeni za Katemera wa mRNA, kusonyeza kudzipereka kwathu pakuchita bwino kwambiri komanso kuchita zinthu zatsopano. Kupita patsogolo kwaukadaulo uku kumapitilira kuyankha kwa mliri pakupanga katemera wa matenda obwera chifukwa cha ma virus. Chifukwa chake, ndiukadaulo wathu, TECNIC ikuyala maziko a mtsogolo momwe kupewa ndi kuchiza matenda ndikosavuta komanso kothandiza kuposa kale.

Pomaliza, nkhaniyi ikuwonetsa kufunikira kwa bioreactors mu biotechnology ndi TECNICNtchito yothana ndi zovuta zazaumoyo ndikuwunika zaukadaulo komanso kukhazikika.

Zokhudzana Zokhudzana

amagwira

amagwira

Zikubwera posachedwa 

Tikumaliza tsatanetsatane wa zida zathu zatsopano. Posachedwapa, tidzalengeza zosintha zonse. Ngati mukufuna kulandira nkhani zaposachedwa kwambiri pazamalonda athu, lembetsani ku nyuzipepala yathu kapena tsatirani njira zathu zapa media. 

Fomu Yamakalata

Lowani

Khalani infodziwani zaukadaulo wazogulitsa, machitidwe abwino, zochitika zosangalatsa ndi zina zambiri! Pambuyo polembetsa kalata yathu yamakalata, mutha kusiya kulembetsa nthawi iliyonse.

Fomu Yamakalata

Rushton mphepo

The Rushton impeller, yomwe imadziwikanso kuti flat disk impeller. Zinatuluka ngati njira yothetsera vutoli zovuta zosakanikirana ndi okosijeni mumakampani a biotechnology. Kapangidwe kake katsopano kadadziwika mwachangu chifukwa cha kuthekera kwake kotulutsa chipwirikiti, ndikupangitsa kuti ikhale muyezo mu gawoli kwazaka zambiri.

Zokonzedwa Kwambiri
Mapulogalamu mu Biotechnology
Ubwino Wochita Mwachangu
Kukhalitsa ndi Kudalirika
Kukhathamiritsa kwa TECNIC

Pitch blade mphepo

Chigawochi ndi chofunikira kwambiri pakuwongolera kusakanikirana ndi kusamutsa anthu ambiri muzochita zama cell. Mapangidwe ake enieni amathandizira kugawa kofanana kwa zakudya ndi mpweya, zomwe ndizofunikira kuti ma cell azikhala ndi mphamvu komanso kukula pansi pamikhalidwe yabwino.

Zokonzedwa Kwambiri
Mapulogalamu mu Biotechnology
Ubwino Wochita Mwachangu
Kukhalitsa ndi Kudalirika

Rushton mphepo

Amadziwika ndi masamba ake ozungulira omwe amayikidwa molunjika ku shaft, the Rushton impeller imapangidwa kuti ipereke mitengo yometa ubweya wambiri komanso kubalalika kwabwino kwambiri kwa gasi, komwe kumakhala kothandiza kwambiri pazachilengedwe. Mu biotechnological ntchito zophatikiza mabakiteriya ndi yisiti, the Rushton impeller imapambana powonetsetsa kusakanikirana kofanana ndi kugawa bwino gasi, ngakhale m'zikhalidwe zokhala ndi kachulukidwe kwambiri.

Zokonzedwa Kwambiri
Mapulogalamu mu Biotechnology
Ubwino Wochita Mwachangu
Kukhalitsa ndi Kudalirika

Cassette

Timamvetsetsa kufunikira kwa kusinthasintha komanso kuchita bwino munjira za labotale. Ndichifukwa chake zida zathu zidapangidwa kuti zizigwirizana nazo Cassette Mafayilo, yankho lapamwamba la ntchito zosiyanasiyana zosefera. Ngakhale sitipanga zosefera mwachindunji, makina athu amakometsedwa kuti agwiritse ntchito phindu lonse Cassette Zosefera zimapereka.

Cassette Zosefera zimadziwika chifukwa cha kusefera kwakukulu komanso kuchita bwino pakupatukana, kuwapanga kukhala abwino ultrafiltration, microfiltration, ndi nanofiltration ntchito. Mwa kuphatikiza zoseferazi mu zida zathu, timathandizira njira zofulumira komanso zogwira mtima, ndikuwonetsetsa kuti pakhale zotsatira zabwino kwambiri.

zida zathu, kukhala n'zogwirizana ndi Cassette zosefera, zimapereka kusinthasintha kwakukulu komanso kusinthasintha. Izi zikutanthauza kuti mutha kusankha fyuluta yomwe ikugwirizana ndi zosowa zanu zenizeni, kuwonetsetsa kuti kuyesa kulikonse kapena kupanga kumachitika mwachangu komanso molondola.

Kuphatikiza apo, zida zathu ndizodziwika bwino 100% automation luso. Pogwiritsa ntchito mavavu apamwamba kwambiri, timatsimikizira kuwongolera kolondola kusiyana kwa kuthamanga, kuthamanga kwa transmembrane, ndi kuthamanga kwa magazi. izi automation sikuti imangowonjezera luso komanso kulondola kwa kusefera komanso kumachepetsa kwambiri kulowererapo pamanja, kupanga makina athu odalirika komanso osavuta kugwiritsa ntchito.

Hollow Fiber

Timazindikira udindo wofunikira kwambiri wosinthika komanso wogwira ntchito bwino m'ma laboratories. Ichi ndichifukwa chake zida zathu zidapangidwa mwaluso kuti zizigwirizana nazo Hollow Fiber Mafayilo, kupereka yankho lapamwamba la ntchito zambiri zosefera. Ngakhale kuti sitimapanga zosefera izi mwachindunji, makina athu amawunikidwa bwino kuti agwiritse ntchito zonse zomwe angathe Hollow Fiber mafayilo.

Hollow Fiber Zosefera ndizodziwikiratu chifukwa chochita bwino kwambiri pakusefera bwino komanso kuchuluka kwake. Ndiwothandiza makamaka pamapulogalamu omwe amafunikira kuwongolera mofatsa kwa zitsanzo, monga mu chikhalidwe cha ma cell ndi njira zodziwika bwino za biomolecular. Pophatikiza zosefera izi ndi zida zathu, timathandiza njira zosefera bwino, zachangu, komanso zapamwamba kwambiri.

Chomwe chimasiyanitsa zida zathu ndi zake 100% automation luso. Pogwiritsa ntchito ma valve ofananira bwino, makina athu amawongolera mosamala kusiyana kwa kuthamanga, kuthamanga kwa transmembrane, ndi kuthamanga kwa magazi. Level iyi ya automation sikuti imangowonjezera luso komanso kulondola kwa kusefera komanso kumachepetsa kufunika koyang'anira pamanja, kupangitsa makina athu kukhala odalirika komanso osavuta kugwiritsa ntchito.

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