Novembala 28, 2023

Gene ndi ma cell therapy amapereka chiyembekezo chatsopano chamankhwala

Gene ndi chithandizo cha ma cell chapita patsogolo kwambiri pazamankhwala, ndikupereka kupita patsogolo komwe kungasinthe miyoyo ya anthu mamiliyoni ambiri omwe ali ndi matenda obadwa nawo komanso osokonekera. Kupita patsogolo kumeneku kukubweretsa nyengo yatsopano yochiza matenda omwe kale ankawaona kuti ndi osachiritsika.

Cell therapy: kubwezeretsa thanzi ndi ma cell olowerera

Chithandizo cha ma cell, chomwe ndi gawo lamankhwala obwezeretsanso, chimapereka chiyembekezo kwa omwe ali ndi matenda osatha komanso osokonekera. Njirayi imagwiritsa ntchito tsinde kapena ma cell apadera kuchiza, kusintha, kapena kukonzanso minofu ndi ziwalo zowonongeka. Padziko lonse lapansi, ochita kafukufuku amapanga maphunziro omwe amapereka zotsatira zabwino.

Kupambana kwakukulu ndiko kugwiritsa ntchito imaselo amtundu wa pluripotent stem cell (iPSCs) kwa matenda a mtima. Magulu asandutsa ma cell a khungu la odwala kukhala ma tsinde maselo kenako kukhala ma cell amtima omwe amagwira ntchito. Akalowetsedwanso mu mtima, maselowa amabwezeretsa kugwira ntchito kwake ndikuwonjezera moyo wa odwala.

Kuphatikiza apo, chithandizo cha ma cell chathandiza bwino matenda osokonekera. Stem cell ⇀ kuwongolera kwachedwetsa kukula kwa matenda ndikuchepetsa zizindikiro za odwala omwe akuyesedwa.

Kuthana ndi zovuta ndikupititsa patsogolo chithandizo cha jini ndi ma cell

Ngakhale kupita patsogolo kwa jini ndi ma cell therapy kukuwonetsa kudumpha kwakukulu muzamankhwala, pali zovuta zazikulu. Kuwunika kwa chitetezo cha nthawi yayitali komanso kuchita bwino mwa mankhwalawa amafunikira mayeso ozama azachipatala ndi maphunziro.

Komanso, kupangitsa kuti machiritso atsopanowa apezeke ndikofunikira. Ndi kukwera mtengo kwa kafukufuku ndi chitukuko, kupeza njira zoperekera mankhwalawa kwa odwala onse ndikofunikira, mosasamala kanthu za chuma.

Komabe, kupita patsogolo kumeneku kukulozera mtsogolo momwe tingachiritsire kapena kuchiza matenda omwe kale anali osachiritsika. Mgwirizano pakati pa asayansi, mabungwe azachipatala, ndi maboma ndiwofunikira kuti athandizire osowa, kupereka chiyembekezo kwa odwala ndi mabanja padziko lonse lapansi.

Kupititsa patsogolo kupezeka ndi mphamvu ya jini ndi ma cell therapy

Pa chithandizo cha ma cell kapena majini, zida zapadera ndi matekinoloje ndizofunikira pakukulitsa ndi kusamalira ma cell osinthidwa. M'lingaliro limeneli, bioreactors amagwira ntchito yofunika kwambiri . Amapereka malo olamulidwa, osabala kuti ma cell akule ex vivo, kuwakulitsa mwaunyinji asanalowetsedwenso mwa wodwalayo. Ma bioreactors amathandizira kukhathamiritsa ma protocol a kulima ndikusunga ma cell achire komanso kutheka.

Komanso, kusefera kwa tangential flow (TFF) ⇀ ukadaulo umagwira ntchito yofunika kwambiri pakupanga ma cell ndi ma gene therapy. TFF, njira yolekanitsira ndi kuika maganizo, imayeretsa maselo ochizira ndikuchotsa zonyansa. Izi zimatsimikizira chitetezo ndi mphamvu ya Mlingo woperekedwa. Pogwiritsa ntchito njira yapamwambayi, titha kupeza maselo osinthidwa apamwamba kwambiri, ofunikira kuti chithandizocho chipambane komanso kuti chitetezeke.

Kugwiritsiridwa ntchito kophatikizana kwa bioreactors ndi ukadaulo wa TFF kumawonetsa a kudumpha kwakukulu pakupanga ma gene ndi ma cell therapy. Zimathandizira kupanga kwakukulu kwamankhwalawa, kutsegulira khomo kwa odwala ambiri kuti alandire chithandizo chamankhwala posachedwa.

Zokhudzana Zokhudzana

amagwira

amagwira

Zikubwera posachedwa 

Tikumaliza tsatanetsatane wa zida zathu zatsopano. Posachedwapa, tidzalengeza zosintha zonse. Ngati mukufuna kulandira nkhani zaposachedwa kwambiri pazamalonda athu, lembetsani ku nyuzipepala yathu kapena tsatirani njira zathu zapa media. 

Fomu Yamakalata

Lowani

Khalani infodziwani zaukadaulo wazogulitsa, machitidwe abwino, zochitika zosangalatsa ndi zina zambiri! Pambuyo polembetsa kalata yathu yamakalata, mutha kusiya kulembetsa nthawi iliyonse.

Fomu Yamakalata

Rushton mphepo

The Rushton impeller, yomwe imadziwikanso kuti flat disk impeller. Zinatuluka ngati njira yothetsera vutoli zovuta zosakanikirana ndi okosijeni mumakampani a biotechnology. Kapangidwe kake katsopano kadadziwika mwachangu chifukwa cha kuthekera kwake kotulutsa chipwirikiti, ndikupangitsa kuti ikhale muyezo mu gawoli kwazaka zambiri.

Zokonzedwa Kwambiri
Mapulogalamu mu Biotechnology
Ubwino Wochita Mwachangu
Kukhalitsa ndi Kudalirika
Kukhathamiritsa kwa TECNIC

Pitch blade mphepo

Chigawochi ndi chofunikira kwambiri pakuwongolera kusakanikirana ndi kusamutsa anthu ambiri muzochita zama cell. Mapangidwe ake enieni amathandizira kugawa kofanana kwa zakudya ndi mpweya, zomwe ndizofunikira kuti ma cell azikhala ndi mphamvu komanso kukula pansi pamikhalidwe yabwino.

Zokonzedwa Kwambiri
Mapulogalamu mu Biotechnology
Ubwino Wochita Mwachangu
Kukhalitsa ndi Kudalirika

Rushton mphepo

Amadziwika ndi masamba ake ozungulira omwe amayikidwa molunjika ku shaft, the Rushton impeller imapangidwa kuti ipereke mitengo yometa ubweya wambiri komanso kubalalika kwabwino kwambiri kwa gasi, komwe kumakhala kothandiza kwambiri pazachilengedwe. Mu biotechnological ntchito zophatikiza mabakiteriya ndi yisiti, the Rushton impeller imapambana powonetsetsa kusakanikirana kofanana ndi kugawa bwino gasi, ngakhale m'zikhalidwe zokhala ndi kachulukidwe kwambiri.

Zokonzedwa Kwambiri
Mapulogalamu mu Biotechnology
Ubwino Wochita Mwachangu
Kukhalitsa ndi Kudalirika

Cassette

Timamvetsetsa kufunikira kwa kusinthasintha komanso kuchita bwino munjira za labotale. Ndichifukwa chake zida zathu zidapangidwa kuti zizigwirizana nazo Cassette Mafayilo, yankho lapamwamba la ntchito zosiyanasiyana zosefera. Ngakhale sitipanga zosefera mwachindunji, makina athu amakometsedwa kuti agwiritse ntchito phindu lonse Cassette Zosefera zimapereka.

Cassette Zosefera zimadziwika chifukwa cha kusefera kwakukulu komanso kuchita bwino pakupatukana, kuwapanga kukhala abwino ultrafiltration, microfiltration, ndi nanofiltration ntchito. Mwa kuphatikiza zoseferazi mu zida zathu, timathandizira njira zofulumira komanso zogwira mtima, ndikuwonetsetsa kuti pakhale zotsatira zabwino kwambiri.

zida zathu, kukhala n'zogwirizana ndi Cassette zosefera, zimapereka kusinthasintha kwakukulu komanso kusinthasintha. Izi zikutanthauza kuti mutha kusankha fyuluta yomwe ikugwirizana ndi zosowa zanu zenizeni, kuwonetsetsa kuti kuyesa kulikonse kapena kupanga kumachitika mwachangu komanso molondola.

Kuphatikiza apo, zida zathu ndizodziwika bwino 100% automation luso. Pogwiritsa ntchito mavavu apamwamba kwambiri, timatsimikizira kuwongolera kolondola kusiyana kwa kuthamanga, kuthamanga kwa transmembrane, ndi kuthamanga kwa magazi. izi automation sikuti imangowonjezera luso komanso kulondola kwa kusefera komanso kumachepetsa kwambiri kulowererapo pamanja, kupanga makina athu odalirika komanso osavuta kugwiritsa ntchito.

Hollow Fiber

Timazindikira udindo wofunikira kwambiri wosinthika komanso wogwira ntchito bwino m'ma laboratories. Ichi ndichifukwa chake zida zathu zidapangidwa mwaluso kuti zizigwirizana nazo Hollow Fiber Mafayilo, kupereka yankho lapamwamba la ntchito zambiri zosefera. Ngakhale kuti sitimapanga zosefera izi mwachindunji, makina athu amawunikidwa bwino kuti agwiritse ntchito zonse zomwe angathe Hollow Fiber mafayilo.

Hollow Fiber Zosefera ndizodziwikiratu chifukwa chochita bwino kwambiri pakusefera bwino komanso kuchuluka kwake. Ndiwothandiza makamaka pamapulogalamu omwe amafunikira kuwongolera mofatsa kwa zitsanzo, monga mu chikhalidwe cha ma cell ndi njira zodziwika bwino za biomolecular. Pophatikiza zosefera izi ndi zida zathu, timathandiza njira zosefera bwino, zachangu, komanso zapamwamba kwambiri.

Chomwe chimasiyanitsa zida zathu ndi zake 100% automation luso. Pogwiritsa ntchito ma valve ofananira bwino, makina athu amawongolera mosamala kusiyana kwa kuthamanga, kuthamanga kwa transmembrane, ndi kuthamanga kwa magazi. Level iyi ya automation sikuti imangowonjezera luso komanso kulondola kwa kusefera komanso kumachepetsa kufunika koyang'anira pamanja, kupangitsa makina athu kukhala odalirika komanso osavuta kugwiritsa ntchito.

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