Sinthani Thanzi ndi Ma Viral Vectors & VLPs

Ofufuza padziko lonse amachita khama kupanga ndi kugwiritsa ntchito matekinoloje atsopano zokhudzana ndi ma virus, tinthu tating'onoting'ono tokhala ngati ma virus ndi ma AAV. Zowonjezera izi zitha kusintha kusintha kulimbana ndi matenda ambiri, kubweretsa chiyembekezo chatsopano cha thanzi ndi moyo wabwino.

Kugwiritsa ntchito tizilombo toyambitsa matenda ndi tizilombo toyambitsa matenda tizilombo toyambitsa matenda

Ofufuza padziko lonse lapansi akugwira ntchito mwakhama chitukuko ndi kugwiritsa ntchito matekinoloje atsopano okhudzana ndi ma viral vectors, virus-like particles (VLPs), ndi adeno-associated vaccines (AAVs). Kupititsa patsogolo uku kumalonjeza kusintha polimbana ndi matenda osiyanasiyana, kupereka chiyembekezo chatsopano cha thanzi la munthu.

Ma vector a ma virus amagwira ntchito yofunika kwambiri pakupanga ma jini, amakhala ngati zonyamulira ma genetic kupita ku maselo enaake. Zaka khumi zapitazi zawonetsa kupita patsogolo kwakukulu kwa chitukuko cha ma virus, makamaka AAVs. Ma vectors otetezekawa amapereka bwino majini, kusonyeza lonjezo lochiza matenda osiyanasiyana.

Tinthu tofanana ndi ma virus amafanana ndi ma virus koma alibe DNA yopatsirana, zomwe zimapangitsa kukhala chisankho chodalirika pakupanga katemera. Amayambitsa chitetezo champhamvu, chokhazikika popanda chiopsezo chotenga matenda. Kafukufuku tsopano akufuna kugwiritsa ntchito ma VLPs motsutsana ndi matenda a virus ndi mabakiteriya, komanso khansa.

Ma AAV ayamba kuzindikirika chifukwa cholimbikitsa mayankho olimba, otetezeka a chitetezo chamthupi. Mavairasi opanda vuto amenewa amanyamula chibadwa cha tizilombo toyambitsa matenda kupita m'thupi. Akalowa mkati, amalangiza maselo a chitetezo cha mthupi kupanga mapuloteni omwe amamenyana ndi tizilombo toyambitsa matenda. Njirayi ikulonjeza kupewa matenda komanso kusamalira matenda osachiritsika.

Kusakanikirana kwa ma vector a ma virus, ma VLPs, ndi ma AAV kumabweretsa katemera wotetezeka, wogwira mtima komanso wochizira matenda osiyanasiyana. Magawo ofunikira kwambiri ndi awa:

Katemera wolimbana ndi matenda opatsirana
Gene Theraphy
Oncology

Zovuta monga kukhathamiritsa kupanga ndi kuwongolera mlingo zilipo, koma tsogolo likuwonekera bwino pamakina a ma virus, ma VLP, ndi matekinoloje a AAV. Zatsopanozi zikutifikitsa ku nthawi yachipatala momwe tingapewere, kuchiza, mwinanso kuthetseratu matenda.

Thandizo lopitilira la gulu la asayansi ndi kupita patsogolo kwaukadaulo ndikofunikira. Amayembekezeredwa kwambiri zimakhudza thanzi lapadziko lonse lapansi ndikuthana ndi matenda oopsa.

TecnicMa bioreactors: Kuthandizira kupanga kwakukulu kwa katemera wosinthira ndi machiritso

Kupanga ma virus, ma VLPs, ndi ma AAV pamakampani ndizovuta. Zimafuna zida zapadera zopangira bioprocessing ndi matekinoloje apamwamba. Kukwaniritsa zofunikira zapadziko lonse zamankhwala ndi katemerawa kumasintha kupanga kukhala njira yolondola, yoyendetsedwa bwino.

Ochita masewerawa amagwira ntchito yofunika kwambiri popanga zazikulu, kuwongolera kukula ndi kukula kwa maselo. TecnicMa bioreactors amapambana pamakampani, opangidwa ndiukadaulo waposachedwa komanso wolondola. Amakwaniritsa zofunikira zapadera zopangira ma virus, tinthu tokhala ngati ma virus ndi ma AAV.

Komabe, kupitilira ma bioreactors, tiyeneranso kukhazikitsa matekinoloje apamwamba oyeretsa. Ukadaulo uwu ndi wofunikira pakulekanitsa ndikuyika mamolekyu omwe mukufuna kuchokera ku ma cell ndi zida zina zama media azachikhalidwe. Njira zathu zoyeretsera zimatha kuphatikizirapass chromatography, kusefera, precipitation, ndi njira zina zapaderazi.

At Tecnic, timayamikira kuti kupanga mafakitale ndizovuta, interdiscipkuyesetsa kwamphamvu. Timagwira ntchito limodzi ndi asayansi, mainjiniya, ndi akatswiri owongolera kuti tiwonetsetse kuti mayankho athu a bioreactor ndi matekinoloje amachitidwe amatsatira mfundo zokhwima kwambiri. Kugwirizana kumeneku kumatsimikizira kupezeka kwakukulu kwa matekinoloje olonjezawa kuti akwaniritse zofunikira zaumoyo padziko lonse lapansi.

Ndi kudzipereka kwathu pakupita patsogolo kwaukadaulo komanso kukonza njira mosalekeza, tikufuna Tecnic's mankhwala kukhala chida kulimbana ndi matenda komanso kupititsa patsogolo moyo wabwino padziko lonse lapansi.

Zokhudzana Zokhudzana

amagwira

amagwira

Zikubwera posachedwa 

Tikumaliza tsatanetsatane wa zida zathu zatsopano. Posachedwapa, tidzalengeza zosintha zonse. Ngati mukufuna kulandira nkhani zaposachedwa kwambiri pazamalonda athu, lembetsani ku nyuzipepala yathu kapena tsatirani njira zathu zapa media. 

Fomu Yamakalata

Lowani

Khalani infodziwani zaukadaulo wazogulitsa, machitidwe abwino, zochitika zosangalatsa ndi zina zambiri! Pambuyo polembetsa kalata yathu yamakalata, mutha kusiya kulembetsa nthawi iliyonse.

Fomu Yamakalata

Rushton mphepo

The Rushton impeller, yomwe imadziwikanso kuti flat disk impeller. Zinatuluka ngati njira yothetsera vutoli zovuta zosakanikirana ndi okosijeni mumakampani a biotechnology. Kapangidwe kake katsopano kadadziwika mwachangu chifukwa cha kuthekera kwake kotulutsa chipwirikiti, ndikupangitsa kuti ikhale muyezo mu gawoli kwazaka zambiri.

Zokonzedwa Kwambiri
Mapulogalamu mu Biotechnology
Ubwino Wochita Mwachangu
Kukhalitsa ndi Kudalirika
Kukhathamiritsa kwa TECNIC

Pitch blade mphepo

Chigawochi ndi chofunikira kwambiri pakuwongolera kusakanikirana ndi kusamutsa anthu ambiri muzochita zama cell. Mapangidwe ake enieni amathandizira kugawa kofanana kwa zakudya ndi mpweya, zomwe ndizofunikira kuti ma cell azikhala ndi mphamvu komanso kukula pansi pamikhalidwe yabwino.

Zokonzedwa Kwambiri
Mapulogalamu mu Biotechnology
Ubwino Wochita Mwachangu
Kukhalitsa ndi Kudalirika

Rushton mphepo

Amadziwika ndi masamba ake ozungulira omwe amayikidwa molunjika ku shaft, the Rushton impeller imapangidwa kuti ipereke mitengo yometa ubweya wambiri komanso kubalalika kwabwino kwambiri kwa gasi, komwe kumakhala kothandiza kwambiri pazachilengedwe. Mu biotechnological ntchito zophatikiza mabakiteriya ndi yisiti, the Rushton impeller imapambana powonetsetsa kusakanikirana kofanana ndi kugawa bwino gasi, ngakhale m'zikhalidwe zokhala ndi kachulukidwe kwambiri.

Zokonzedwa Kwambiri
Mapulogalamu mu Biotechnology
Ubwino Wochita Mwachangu
Kukhalitsa ndi Kudalirika

Cassette

Timamvetsetsa kufunikira kwa kusinthasintha komanso kuchita bwino munjira za labotale. Ndichifukwa chake zida zathu zidapangidwa kuti zizigwirizana nazo Cassette Mafayilo, yankho lapamwamba la ntchito zosiyanasiyana zosefera. Ngakhale sitipanga zosefera mwachindunji, makina athu amakometsedwa kuti agwiritse ntchito phindu lonse Cassette Zosefera zimapereka.

Cassette Zosefera zimadziwika chifukwa cha kusefera kwakukulu komanso kuchita bwino pakupatukana, kuwapanga kukhala abwino ultrafiltration, microfiltration, ndi nanofiltration ntchito. Mwa kuphatikiza zoseferazi mu zida zathu, timathandizira njira zofulumira komanso zogwira mtima, ndikuwonetsetsa kuti pakhale zotsatira zabwino kwambiri.

zida zathu, kukhala n'zogwirizana ndi Cassette zosefera, zimapereka kusinthasintha kwakukulu komanso kusinthasintha. Izi zikutanthauza kuti mutha kusankha fyuluta yomwe ikugwirizana ndi zosowa zanu zenizeni, kuwonetsetsa kuti kuyesa kulikonse kapena kupanga kumachitika mwachangu komanso molondola.

Kuphatikiza apo, zida zathu ndizodziwika bwino 100% automation luso. Pogwiritsa ntchito mavavu apamwamba kwambiri, timatsimikizira kuwongolera kolondola kusiyana kwa kuthamanga, kuthamanga kwa transmembrane, ndi kuthamanga kwa magazi. izi automation sikuti imangowonjezera luso komanso kulondola kwa kusefera komanso kumachepetsa kwambiri kulowererapo pamanja, kupanga makina athu odalirika komanso osavuta kugwiritsa ntchito.

Hollow Fiber

Timazindikira udindo wofunikira kwambiri wosinthika komanso wogwira ntchito bwino m'ma laboratories. Ichi ndichifukwa chake zida zathu zidapangidwa mwaluso kuti zizigwirizana nazo Hollow Fiber Mafayilo, kupereka yankho lapamwamba la ntchito zambiri zosefera. Ngakhale kuti sitimapanga zosefera izi mwachindunji, makina athu amawunikidwa bwino kuti agwiritse ntchito zonse zomwe angathe Hollow Fiber mafayilo.

Hollow Fiber Zosefera ndizodziwikiratu chifukwa chochita bwino kwambiri pakusefera bwino komanso kuchuluka kwake. Ndiwothandiza makamaka pamapulogalamu omwe amafunikira kuwongolera mofatsa kwa zitsanzo, monga mu chikhalidwe cha ma cell ndi njira zodziwika bwino za biomolecular. Pophatikiza zosefera izi ndi zida zathu, timathandiza njira zosefera bwino, zachangu, komanso zapamwamba kwambiri.

Chomwe chimasiyanitsa zida zathu ndi zake 100% automation luso. Pogwiritsa ntchito ma valve ofananira bwino, makina athu amawongolera mosamala kusiyana kwa kuthamanga, kuthamanga kwa transmembrane, ndi kuthamanga kwa magazi. Level iyi ya automation sikuti imangowonjezera luso komanso kulondola kwa kusefera komanso kumachepetsa kufunika koyang'anira pamanja, kupangitsa makina athu kukhala odalirika komanso osavuta kugwiritsa ntchito.

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