21 Marichi 2022

VEGA ndi TECNIC: Kupititsa patsogolo muyeso wa bioprocess palimodzi

TECNIC Bioprocess Solutions Partners ndi VEGA ku Advance Measurement Technology mu Bioprocesses

 Tikuyang'anizana ndi nthawi yosangalatsa ya biotechnology. Kuphatikiza pa gawo lokulitsa lomwe likukumana nalo pakali pano, njira zambiri zamankhwala ndi zamankhwala zikusintha kukhala njira zasayansi yazachilengedwe. Pakati pa zosintha zonsezi ndi TECNIC Bioprocess Solutions, yomwe ili ku Girona, makilomita 80 kuchokera mumzinda wa Barcelona, ​​​​imene imathandizira makasitomala ake m'magawo onse a bioprocess. Pankhani yaukadaulo woyezera kuthamanga komanso mulingo, imadalira zida zoyezera za VEGA.

Kampaniyo, yomwe idakhazikitsidwa zaka khumi zapitazo, ikukula mwachangu. Ndi malo opangira 5000 m², TECNIC imayang'anira zida zogwiritsira ntchito biotechnological ndi mankhwala zama laboratories, malo oyendetsa ndege, ndi malo opangira. Ntchito zake zimagwira ntchito yonse yopangira, kuchokera pakupanga ndi zomangamanga za 3D mpaka zida ndi zida zopangira ndi kutumiza. TECNIC ili ndi ma laboratories a BSL2 olima ma cell ndi tizilombo tating'onoting'ono, omwe amagwiritsa ntchito kuthandiza makasitomala. "Timathandiza makasitomala athu pofotokozera zida upstream or downstream ndondomeko, kapena pa nthawi makulitsidwe gawo. Timakhala ngati ulalo pakati pa R&D ndi madipatimenti opanga, kupereka mayankho owopsa kuti apititse patsogolo ntchito zama mafakitale," akufotokoza. TECNICwoyang'anira ntchito.

M'zaka zake zoyambirira, chidwi chinkangoyang'ana kwambiri pazamankhwala, koma mu 2018, dipatimenti yatsopano yaukadaulo wachilengedwe idawonjezedwa. Tsopano, kampaniyo imakhudza njira zonse wamba monga upstream (ie, ma bioreactors kapena kukonzekera kwapakati tanks) ndi downstream (zida zosefera tangential flow). TECNIC amapereka osiyanasiyana zida ⇀ za labotale (eLAB), malo oyendetsa ndege (ePILOT), kapena ntchito zopanga (ePROD). Ma bioreactors ndi zida zomwe zimatengera momwe zinthu zilili bwino pakukula kwa ma cell kapena chikhalidwe cha tizilombo toyambitsa matenda powongolera kutentha, pH, ndi kupanikizika pang'ono kwa okosijeni (pO2), komanso kusungunuka kwa mpweya wosungunuka komanso kachulukidwe kakang'ono (TCD), kachulukidwe ka cell (VCD), kapena kusungunuka CO2. Kuwongolera kwa okosijeni wosungunuka mu chikhalidwe cha chikhalidwe kumatheka, mwachitsanzo, kupyolera mu malamulo a cascade omwe amagwira ntchito zosiyanasiyana monga chipwirikiti, aeration, kapena mpweya wowonjezera mpweya. Kuwonetsetsa kuti sterility mu biological reactor, mavavu owonjezera osabala ndi njira yoyeserera ya aseptic yapangidwa, yomwe imalumikizidwa ndi SIP (Sterilization in Place) dongosolo.

Zosokoneza komanso zowoneka bwino zapa media

Kukhala ndi miyeso yodalirika yoyezera ndi chinthu chofunikira kwambiri pamachitidwe apamwamba. Pankhani yaukadaulo woyezera komanso kuyeza, kampaniyo imadalira masensa a VEGA kuyambira pomwe idayamba kugwira ntchito pazomera za bioprocess zaka zingapo zapitazo. "M'zinthu zambiri, kutentha kumayambira -10 ° C kufika + 140 ° C panthawi yolera yotseketsa. Nthawi zonse timalimbana ndi ma viscous media ndi chipwirikiti, koma nthunzi ndi CIP kuyeretsa kumakhudzanso masensa," akutero, pofotokoza momwe ma bioreactor amapangidwira TECNIC.

Masensa osiyanasiyana

Pazida zawo, pali mitundu yambiri ya masensa a VEGA omwe amaikidwa, omwe, nawonso, amatumiza zizindikiro zawo za analogi ndi digito ku mapulogalamu a eSCADA opangidwa mkati. Pulogalamuyi, yokhala ndi zomangamanga zamafakitale pazida zonse kuphatikiza ma labotale, imayendetsa magawo owongolera ndikukonzanso.cipe kuphedwa motsatira malamulo a CFR21 Part11 (FDA) ndi malangizo a GAMP5. "Timayang'anira kuwongolera ndi kutumiza masensa onse tokha. Kuphatikiza apo, titha kudalira thandizo laukadaulo la VEGA," ndemanga.

VEGABAR 28 ndiye sensor yokhazikika pakuyezera kupanikizika. Ndi chithandizo chake, njira zoletsera mu bioreactors zimayendetsedwa. Sensa ndiyofunikira pakuwonetsetsa kupanikizika kwa mipiringidzo 1.3. VEGABAR 28 ndi sensa yapadziko lonse lapansi yokhala ndi cell yoyezera ya ceramic poyezera mpweya, nthunzi, ndi zakumwa mpaka 130 ° C. Mtima wa sensor yokakamiza ndi cell yoyezera mphamvu, yomwe imasintha kuthamanga kogwiritsidwa ntchito kukhala chizindikiro chamagetsi. Chizindikiro ichi, chodalira kukakamizidwa, chimasinthidwa kukhala chizindikiro chovomerezeka ndi magetsi ophatikizidwa. Sensa ndi cell yotsimikizika ya CERTEC® ceramic yoyezera, yomwe simangopereka kukhazikika kwanthawi yayitali komanso kukana kwambiri. Selo yoyezera ya CERTEC® ndi cell yowuma yopanda mafuta.

VEGABAR 29 ndiyenso, sensa yokhazikika mu zida zosefera tangential flow (TFF), mwachitsanzo, m'magawo oyeretsa a biotechnological process. Sensa imayang'anira TMP (kuthamanga kwa transmembrane), gawo lofunikira pakusefera. Izi ndondomeko chizindikiro ndi kuthamanga pafupifupi wa chakudya otaya pa permeate mbali ya nembanemba. TECNIC's tangential flow filtration (TFF) pamitundu yonse ya zida ndi yokwanira automated, kulola kuti TMP idziwiketu, ndipo ndondomekoyi ikhoza kuwongoleredwa pochita pa valavu.

Kampaniyo nthawi zina imagwiritsa ntchito kafukufuku woyezera ndodo ya VEGACAL 62, koma imayamikiridwa kwambiri. CIP (Cleaning in Place) machitidwe chifukwa cha kukana kwake kwa mankhwala. Imayesa mlingo mosalekeza panthawiyi. Kumbali inayi, VEGAFLEX 81 (sensor yowongolera radar) imagwiritsidwa ntchito pafupipafupi pazigawo zosiyanasiyana, mwachitsanzo, kuyeza mulingo wa kusefera kwa tangential. tanks, pomwe kuyeza kwamtengo wapamwamba kumafunikira pakuwongolera njira zodalirika.

VEGAPOINT 11 ndi VEGAPOINT 23 masiwichi amawunivesite amawunika mulingo pamalo onse pomwe miyezo ya ASME-BPE, EHEDG, kapena GMP iyenera kukwaniritsidwa, mwachitsanzo, mdera la mpope. Masensa awa amagwiranso ntchito bwino pakutsekereza njira. Chifukwa cha kulumikizana kwawo konsekonse kwa ma adapter aukhondo, ndalama zoyikapo ndizochepa. Masensa amathanso kugwiritsidwa ntchito pakugwiritsa ntchito popanda kusintha.

The compact radar sensor VEGAPULS 21, yomwe imathandizanso CIP Njira zofikira ku 80 ° C, zimagwiritsidwa ntchito poyang'anira kuchuluka kosafunikira komwe sikufuna kulumikizana ndi chinthucho. Ngati mulingo uyenera kulembedwa molondola kwambiri komanso osalumikizana ndi chinthucho, chisankho chabwino kwambiri ndi VEGAPULS 64, chomwe chimayang'anira ma voliyumu ovuta kwambiri. Sensa iyi ya 80 GHz radar yoyezera mosalekeza muzamadzimadzi ndiyoyeneranso SIP njira.

Pomaliza, masiwichi a VEGASWING 51 ndi VEGASWING 61 ogwedera amayikidwa nthawi zambiri, makamaka m'mapulogalamu omwe ASME-BPE, EHEDG, kapena GMP sagwiritsidwa ntchito.

Kuyamikira kwakukulu kwa utumiki ndi chithandizo

"Chomwe timachikonda kwambiri ndi kudalirika kwa masensa a VEGA. Komabe, kwa ife, utumiki komanso, koposa zonse, VEGA's. thandizo laukadaulo padziko lonse lapansi ndizofunikira kwambiri, chifukwa timagulitsa zida zathu za bioprocess padziko lonse lapansi," akutero. Ponena za kukhazikitsa, adachita chidwi ndi kulumikizana kwa Bluetooth kwa masensa. Kuphatikiza apo, kusagwirizana kungadziwikenso mwachangu m'zochita zatsiku ndi tsiku," akufotokoza zomwe adakumana nazo.

Zokhudzana Zokhudzana

amagwira

amagwira

Zikubwera posachedwa 

Tikumaliza tsatanetsatane wa zida zathu zatsopano. Posachedwapa, tidzalengeza zosintha zonse. Ngati mukufuna kulandira nkhani zaposachedwa kwambiri pazamalonda athu, lembetsani ku nyuzipepala yathu kapena tsatirani njira zathu zapa media. 

Fomu Yamakalata

Lowani

Khalani infodziwani zaukadaulo wazogulitsa, machitidwe abwino, zochitika zosangalatsa ndi zina zambiri! Pambuyo polembetsa kalata yathu yamakalata, mutha kusiya kulembetsa nthawi iliyonse.

Fomu Yamakalata

Rushton mphepo

The Rushton impeller, yomwe imadziwikanso kuti flat disk impeller. Zinatuluka ngati njira yothetsera vutoli zovuta zosakanikirana ndi okosijeni mumakampani a biotechnology. Kapangidwe kake katsopano kadadziwika mwachangu chifukwa cha kuthekera kwake kotulutsa chipwirikiti, ndikupangitsa kuti ikhale muyezo mu gawoli kwazaka zambiri.

Zokonzedwa Kwambiri
Mapulogalamu mu Biotechnology
Ubwino Wochita Mwachangu
Kukhalitsa ndi Kudalirika
Kukhathamiritsa kwa TECNIC

Pitch blade mphepo

Chigawochi ndi chofunikira kwambiri pakuwongolera kusakanikirana ndi kusamutsa anthu ambiri muzochita zama cell. Mapangidwe ake enieni amathandizira kugawa kofanana kwa zakudya ndi mpweya, zomwe ndizofunikira kuti ma cell azikhala ndi mphamvu komanso kukula pansi pamikhalidwe yabwino.

Zokonzedwa Kwambiri
Mapulogalamu mu Biotechnology
Ubwino Wochita Mwachangu
Kukhalitsa ndi Kudalirika

Rushton mphepo

Amadziwika ndi masamba ake ozungulira omwe amayikidwa molunjika ku shaft, the Rushton impeller imapangidwa kuti ipereke mitengo yometa ubweya wambiri komanso kubalalika kwabwino kwambiri kwa gasi, komwe kumakhala kothandiza kwambiri pazachilengedwe. Mu biotechnological ntchito zophatikiza mabakiteriya ndi yisiti, the Rushton impeller imapambana powonetsetsa kusakanikirana kofanana ndi kugawa bwino gasi, ngakhale m'zikhalidwe zokhala ndi kachulukidwe kwambiri.

Zokonzedwa Kwambiri
Mapulogalamu mu Biotechnology
Ubwino Wochita Mwachangu
Kukhalitsa ndi Kudalirika

Cassette

Timamvetsetsa kufunikira kwa kusinthasintha komanso kuchita bwino munjira za labotale. Ndichifukwa chake zida zathu zidapangidwa kuti zizigwirizana nazo Cassette Mafayilo, yankho lapamwamba la ntchito zosiyanasiyana zosefera. Ngakhale sitipanga zosefera mwachindunji, makina athu amakometsedwa kuti agwiritse ntchito phindu lonse Cassette Zosefera zimapereka.

Cassette Zosefera zimadziwika chifukwa cha kusefera kwakukulu komanso kuchita bwino pakupatukana, kuwapanga kukhala abwino ultrafiltration, microfiltration, ndi nanofiltration ntchito. Mwa kuphatikiza zoseferazi mu zida zathu, timathandizira njira zofulumira komanso zogwira mtima, ndikuwonetsetsa kuti pakhale zotsatira zabwino kwambiri.

zida zathu, kukhala n'zogwirizana ndi Cassette zosefera, zimapereka kusinthasintha kwakukulu komanso kusinthasintha. Izi zikutanthauza kuti mutha kusankha fyuluta yomwe ikugwirizana ndi zosowa zanu zenizeni, kuwonetsetsa kuti kuyesa kulikonse kapena kupanga kumachitika mwachangu komanso molondola.

Kuphatikiza apo, zida zathu ndizodziwika bwino 100% automation luso. Pogwiritsa ntchito mavavu apamwamba kwambiri, timatsimikizira kuwongolera kolondola kusiyana kwa kuthamanga, kuthamanga kwa transmembrane, ndi kuthamanga kwa magazi. izi automation sikuti imangowonjezera luso komanso kulondola kwa kusefera komanso kumachepetsa kwambiri kulowererapo pamanja, kupanga makina athu odalirika komanso osavuta kugwiritsa ntchito.

Hollow Fiber

Timazindikira udindo wofunikira kwambiri wosinthika komanso wogwira ntchito bwino m'ma laboratories. Ichi ndichifukwa chake zida zathu zidapangidwa mwaluso kuti zizigwirizana nazo Hollow Fiber Mafayilo, kupereka yankho lapamwamba la ntchito zambiri zosefera. Ngakhale kuti sitimapanga zosefera izi mwachindunji, makina athu amawunikidwa bwino kuti agwiritse ntchito zonse zomwe angathe Hollow Fiber mafayilo.

Hollow Fiber Zosefera ndizodziwikiratu chifukwa chochita bwino kwambiri pakusefera bwino komanso kuchuluka kwake. Ndiwothandiza makamaka pamapulogalamu omwe amafunikira kuwongolera mofatsa kwa zitsanzo, monga mu chikhalidwe cha ma cell ndi njira zodziwika bwino za biomolecular. Pophatikiza zosefera izi ndi zida zathu, timathandiza njira zosefera bwino, zachangu, komanso zapamwamba kwambiri.

Chomwe chimasiyanitsa zida zathu ndi zake 100% automation luso. Pogwiritsa ntchito ma valve ofananira bwino, makina athu amawongolera mosamala kusiyana kwa kuthamanga, kuthamanga kwa transmembrane, ndi kuthamanga kwa magazi. Level iyi ya automation sikuti imangowonjezera luso komanso kulondola kwa kusefera komanso kumachepetsa kufunika koyang'anira pamanja, kupangitsa makina athu kukhala odalirika komanso osavuta kugwiritsa ntchito.

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