Kukura kwezvinhu zvinosimudzira sei bioreactors

Kukura zvinhu tora nzvimbo yepakati mumunda we bioreactor masisitimu, sezvo ivo vachibatsira kukurudzira kukura kwesero, kuwanda uye kusiyanisa kuwedzera zvakanyanya kugadzirwa kwemaseru anodiwa kana matishu. Nzira dzakasiyana-siyana dzakabuda munzvimbo yebioreactor tekinoroji, imwe neimwe ichipa nzira nyowani dzekubatanidza isina musono yekukura zvinhu mune aya masisitimu:

Ndezvipi zvinhu zvinokura?

Kukura zvinhu mapuroteni iyo inoita basa rakakosha mukukurudzira kukura kwesero, kuwanda uye kusiyanisa. Ivo vanoita nekusunga kune chaiwo ma receptors pane sero pamusoro, zvichikonzeresa maitiro akakosha pakuvandudza uye kugadzirisa kwematishu mumuviri. Aya mapuroteni akakosha pakuchengetedza zvakajairika sero kushanda uye kufambisa kupora kwetishu uye kuvandudzwa mukupindura kukuvara kana chirwere.

Mu biotechnology, kukura zvinhu zviri yakakosha pakugadzirisa magariro emasero mune bioreactors, kwaanoshandiswa kudzora uye kuwedzera kugadzirwa kweakananga maseru kana zvigadzirwa zvebiological. Kushandiswa kwavo chaiko kunogonesa kudzokororwa kwemamiriro ezvinhu anokurudzira anobudirira uye akafanana kukura kwesero, izvo zvakakosha pakugadzirwa kwakakura kwekurapa kwepamusoro nemishonga. Iko kubatanidzwa kwezvinhu zvekukura mubioreactor masisitimu kunosimbisa kukosha kwavo mune yazvino biotechnology uye biopharmaceutical indasitiri.

Mukuwedzera, zvinhu zvekukura zvinoita basa rakakosha mu regenerative mushonga, bazi rinotarisa kuporesa kana kutsiva matishu akakuvadzwa uye nhengo kuburikidza nekushandiswa kwesero kurapa uye biomaterials. Iwo akakosha zvikamu muinjiniya yetishu, uko mashandisiro awo chaiwo anogona kutungamira kuumbwa kwetishu kuita matatu-dimensional zvimiro. Izvi zvinovhura mikana yekurapa huwandu hwakawanda hwezvirwere zvisingaperi uye kukuvara, kubva pakuvandudzwa kweganda kusvika pakugadzirisa nhengo. Kugona kushandura uye kushandisa zvinhu izvi zvinokura mumakiriniki kushandura zvinotarisirwa kupora muvarwere vane mamiriro aimboonekwa seasingarapike.

Matanho ekubatanidza kukura kwezvinhu mu bioreactors

  • Kuwedzera kwakananga: Ingo suma zvinhu zvekukura mune iyo bioreactor's tsika yepakati.
  • encapsulation: Encapsulate kukura zvinhu mukati mebiocompatible zvinhu, senge hydrogel kana microspheres, usati wazvisuma muiyo bioreactor.
  • Genetic Injiniya: Genetic mainjiniya maseru kuburitsa uye kuburitsa zvinhu zvinokura zvakananga mutsika yepakati, kuve nechokwadi chekuenderera mberi kwekugadzirwa mukati menguva yetsika.
  • Surface Immobilization: Batanidza kukura kwezvinhu kune scaffold nzvimbo kana bioreactor zvikamu.

Sarudzo yenzira yekubatanidza kukura kwezvinhu mubioreactor masisitimu zvinoenderana nezvinhu zvakaita se chaiyo application, inodiwa kusunungurwa kinetics, uye kuenderana nemaseru akagadzirwa kana matishu. Kugadzirisa nzira yekutumira kwakakosha kuve nechokwadi chekushandiswa kwakanaka uye kunoshanda kwekukura kwezvinhu mukusimudzira kukura kwesero uye kukura kwetishu mukati meiyo bioreactor system.

TECNIC's Laboratory Bioreactors

Bioreactors yakakosha kune bioprocesses, kunyanya mune biopharmaceutical industry, uko zvinhu zvakakosha zvinobva kune tupukanana. Dhizaini yeaya masisitimu akakosha kuti uwane mhedzisiro yaunoda, sezvo zviri mukati mebioreactors umo hutachiona hunobereka, kukura, kushanda, uye kuzadzisa basa ravo. Izvi zvinosimbisa iyo kukosha kwekutsvakurudza kwakadzama mukugadzira michina inopa mamiriro akakwana ezvipembenene.

At TECNIC, tinopa mhinduro dzinokupa iwe simba, kutanga kubva pabhenji rako rerabhoritari kusvika kune yakazara-chiyero kugadzirwa. Unogona kutanga shanda nemavhoriyamu anotangira pa1 kusvika ku5 litres, autokusanganisa iyo yese yekugadzira maitiro, nekudaro kufambisa basa rako. Chinangwa chedu ndechekutsigira vaongorori uye nyanzvi dzebiotechnology nekuvashongedza nemidziyo inodiwa kuti vakwanise kuwana mhedzisiro nemazvo uye pasi pemamiriro akadzorwa.

Hunhu hutongi hwakakosha muindasitiri, kunyanya kana uchishanda nayo kukura chinhu zvigadzirwa mu immunotherapy tsvakurudzo. Hunhu hwemapuroteni anodzokororwa anogadzirwa mu vitro anogona kusiyanisa nekuda kwemhando dzakasiyana siyana, kubva kune yakasvibira yemhando yemhando kusvika kugadzirisa kusawirirana. TECNIC midziyo inogadzirwa pasi pekutevedzera GMP, kuve nechokwadi chekuchengetedzwa kwepamusoro, kuchena, kugadzikana, uye kushanda nesimba kusimudzira kurapa kwemishonga yekutsvaga uye kukurumidza kubvumidzwa kwepasirese kubvumidzwa kwezvigadzirwa zvebiological. Isu tinopa bioreactors muzviyero zvakasiyana, kugadzira nezvinodiwa kune yega yega maitiro.

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Tiri kupedzisa mashoko emidziyo yedu mitsva. Munguva pfupi, tichazivisa zvese zvinogadziridzwa. Kana iwe uchida kugamuchira zvese zvichangoburwa nezve zvigadzirwa zvedu, nyorera kune yedu tsamba yenhau kana kutevedzera yedu social media chiteshi. 

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Cassette

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Chii chinosiyanisa midziyo yedu ndeye 100% automation kugona. Kuburikidza nekushandiswa kweakaomesesa proportional mavharuvhu, masisitimu edu anowana kudzora zvine hungwaru kusiyana kwekumanikidzwa, transmembrane pressure, uye kuyerera kwehuwandu. Level iyi ye automation haingokwidzi kushanda uye iko kurongeka kwesefa asi zvakare inoderedza zvakanyanya kukosha kwekutarisa nemanyorero, ichipa masisitimu edu akavimbika uye ane hushamwari mushandisi.

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