10 kusvika Chikunguru 2024

Kurapwa kweAlzheimer kutsva kunotenderwa neFDA

A itsva Kurapa kweAlzheimer kunounza tariro kumamiriyoni anobatwa nechirwere ichi. Iyo FDA ichangobva kubvumidza Kisunla (donanemab-azbt) yevakuru mumatanho ekutanga eAlzheimer's. Mvumo iyi ndeye kufambira mberi kwakakosha mukurwisa Alzheimer's, ichipa sarudzo nyowani yekubatsira kunonoka kufambira mberi kwechirwere.

Chii chinonzi chirwere cheAlzheimer?

Alzheimer's chirwere chepfungwa zvinobata mamiriyoni evanhu pasi rose. Zvinotungamirira kukurasikirwa nendangariro uye kufunga kunetseka, pakupedzisira kupindira mumabasa ezuva nezuva. Ndiyo nzira yakajairika yedementia uye inowanzobata vanhu vakura. Chirwere ichi chinoratidzwa nekuvakwa kwebeta amyloid plaques uye tangled fibers muuropi, zvichikonzera matambudziko ekurangarira, kuvhiringidzika, uye kuchinja kwemaitiro.

Zviratidzo uye kufambira mberi

Zviratidzo zvepakutanga zvinosanganisira dambudziko rekuyeuka munguva pfupi yapfuura information uye kunzwa kuvhiringidzika. Sezvo hosha yacho inowedzera, inokonzera zvinetso zvemutauro, kuvhiringidzika kukuru, kuchinja kwemafungiro nemaitiro, uye kurasikirwa kweunyanzvi hwemotokari. Zviratidzo izvi zvinoita kuti hupenyu hwezuva nezuva huome kune avo vanobatwa.

FDA inobvumidza kurapwa kutsva kwechirwere cheAlzheimer

Musi waChikunguru 6, 2024, iyo FDA yakabvumidza Kisunla (donanemab-azbt) yekurapa vanhu vakuru vane danho rekutanga reAlzheimer's. Mushonga uyu, wakagadzirwa naEli Lilly, unopihwa kuburikidza nemwedzi nemwedzi intravenous infusions. Yakaratidzwa kuderedza beta amyloid plaques muuropi, kuderedza kuderera kwekuziva uye kugona kushanda. Mvumo iyi inosanganisira vanhu vane mild cognitive impairment (MCI) uye avo vanorarama nekutanga kweAlzheimer's disease.

Mushonga mutsva weAlzheimer uyu unoshanda sei?

Kisunla is anti-amyloid monoclonal antibody iyo inotarisa amyloid plaques muuropi uye inobatsira kuabvisa. Miedzo yemakiriniki yakaratidza kuti varwere paKisunla vaive nekudzikira zvishoma mukuziva uye kugona kwekuita zvichienzaniswa neavo vari pa placebo. Mushonga kuderedza kufambira mberi kwekiriniki ne35% uye inimabasa ezuva nezuva akavandudzwa ne40% muvarwere vane mazinga epakati etau, puroteni inobatanidza neuronal kukuvara.

Zvinoreva ramangwana

Kubvumidzwa kweKisunla inhanho hombe kumberi mukati kurapa chirwere cheAlzheimer. Inopa nzira itsva yekurapa iyo inogona kuvandudza hupenyu hwevarwere nemhuri dzavo. Kufambira mberi uku kunoratidza kudiwa kwekuenderera mberi nekutsvaga nemasangano kuti vawane marapirwo anoshanda.

Miedzo yemakiriniki uye kuchengeteka

Mune miedzo yekiriniki, chikamucipmasvosve akaongororwa pachishandiswa bvunzo dzakasiyana se Clinical Dementia Rating Scale (CDR-SB) uye iyo ADAS-Cog13 cognitive basa bvunzo.. Kisunla yakaderedza tau mazinga mucerebrospinal fluid uye PET scan biomarkers. Mhedzisiro yakajairika yaive maitiro epainfusion saiti, musoro, uye dzungu. Paivawo nezviitiko zvekuzvimba kweuropi uye kubuda ropa kuduku muuropi, izvo zvakanyatsoongororwa. Ngozi yekuva nemhedzisiro iyi inogona kutariswa nekutarisa kwakaringana.

Kubvumirwa muEuropean Union

Kunyangwe Kisunla yakabvumidzwa neFDA muUnited States, haisati yatenderwa muEuropean Union. Mushure memvumo yeFDA, makambani emishonga anowanzo tsvaga mvumo kubva kune mamwe masangano anodzora, seEuropean Medicines Agency (EMA), kune mamwe misika.

mhedziso

Kubvumidzwa kweFDA kweKisunla chiitiko chakakosha mukurapa kweAlzheimer, ichipa tariro kune avo vari kurwara nechirwere ichi chinonetsa. Kurapa kutsva uku kunogona kunonoka kufambira mberi kwechirwere uye kugadzirisa hupenyu hwevarwere. For more information, ndapota shanyira iyo FDA uye Webhusaiti yaEli Lilly pamisoro iyi.

Related Content

dzokorora

dzokorora

Kuuya manje manje 

Tiri kupedzisa mashoko emidziyo yedu mitsva. Munguva pfupi, tichazivisa zvese zvinogadziridzwa. Kana iwe uchida kugamuchira zvese zvichangoburwa nezve zvigadzirwa zvedu, nyorera kune yedu tsamba yenhau kana kutevedzera yedu social media chiteshi. 

Newsletter Form

Nyorera

gara informed nezve zvigadzirwa zvedu zvitsva, maitiro akanakisa, zviitiko zvinonakidza uye zvimwe zvakawanda! Mushure mekusaina kutsamba yedu, unogona kuzvibvisa chero nguva.

Newsletter Form

Rushton denga

The Rushton impeller, inozivikanwawo se flat disk impeller. Yakabuda semhinduro kune matambudziko ekusanganisa uye oxygenation muindasitiri yebiotechnology. Dhizaini yayo yehunyanzvi yakakurumidza kuzivikanwa nekuda kwekugona kwayo kuburitsa kutenderera kuyerera, zvichiita kuti ive chiyero muchikamu kwemakumi emakore.

Unique Design
Zvishandiso muBiotechnology
Zvakanakira Kubudirira
Kugara uye Kuvimbika
Optimization for TECNIC

Pitch blade denga

Ichi chikamu chakakosha pakugadzirisa kusanganisa uye kuendesa hukuru mumasero tsika maitiro. Yayo chaiyo dhizaini inogonesa kugovaniswa kwezvinovaka muviri uye magasi, zvakakosha pakuchengetedza sero kushanda uye kukura pasi pemamiriro akanyanya.

Unique Design
Zvishandiso muBiotechnology
Zvakanakira Kubudirira
Kugara uye Kuvimbika

Rushton denga

Inoratidzwa neayo radial blades akaiswa perpendicularly kune shaft, iyo Rushton impeller inogadzirwa kuti ipe yakakwirira shear mazinga uye yakanakisa gasi kupararira, iyo inonyanya kushanda mumicrobial. Mune biotechnological application inosanganisira mabhakitiriya uye mbiriso, iyo Rushton impeller inokunda nekuita kuti homogeneous kusanganiswa uye kugovera gasi kwakaringana, kunyangwe mutsika dzakasimba.

Unique Design
Zvishandiso muBiotechnology
Zvakanakira Kubudirira
Kugara uye Kuvimbika

Cassette

Isu tinonzwisisa kukosha kwekushanduka uye kushanda zvakanaka mumarabhoritari maitiro. Ndicho chikonzero midziyo yedu yakagadzirirwa kuti ienderane nayo Cassette Filters, mhinduro yepamusoro yezvakasiyana-siyana zvefiltration application. Kunyangwe isu tisingagadziri mafirita zvakananga, masisitimu edu anogadziridzwa kuti atore mukana wakazara wemabhenefiti ayo Cassette mafirita anopa.

Cassette mafirita anozivikanwa nekukwira kwawo kwesefa uye kugona mukuparadzanisa, achiaita akanakira Ultrafiltration, microfiltration, uye nanofiltration application. Nekubatanidza mafirita aya mumidziyo yedu, tinofambisa maitiro anokurumidza uye anoshanda, tichiona mhedzisiro yemhando yepamusoro.

Midziyo yedu, kuenderana nayo Cassette mafirita, inopa hukuru hwekusiyana-siyana uye kuchinjika. Izvi zvinoreva kuti iwe unogona kusarudza sefa inonyatso kuenderana nezvido zvako, kuve nechokwadi chekuti kuyedza kwega kwega kana maitiro ekugadzira anoitwa nekunyatsogona uye nemazvo.

Uyezve, midziyo yedu inomira kunze kwayo 100% automation kugona. Tichishandisa advanced proportional mavharuvhu, isu nechokwadi chaiyo kudzora pamusoro kusiyana kwekumanikidzwa, transmembrane pressure, uye kuyerera kwehuwandu. ichi automation haingowedzere kushanda uye kurongeka kwekusefa asi zvakare inoderedza zvakanyanya kupindira kwemanyorero, zvichiita kuti masisitimu edu avimbike zvakanyanya uye mushandisi-ane hushamwari.

Hollow Fiber

Isu tinocherekedza basa rakakosha rekuchinjika uye kugona mumarabhoritari maitiro. Ndicho chikonzero midziyo yedu yakagadzirwa zvine hungwaru kuti ienderane nayo Hollow Fiber Filters, ichipa mhinduro yepamusoro kune yakafara spectrum yekusefa maapplication. Kunyange isu tisingagadziri masefa aya zvakanangana, masisitimu edu akakwenenzverwa kuti ashandise kugona kwakazara kwe Hollow Fiber filters.

Hollow Fiber mafirita anozivikanwa nekuita kwawo kwakasarudzika maererano nekusefa kwakanaka uye kugona. Iwo anonyanya kushanda kune maapplication anoda kubatwa zvinyoro nyoro kwemasamples, senge musero tsika uye sensitive biomolecular process. Nekubatanidza mafirita aya nemidziyo yedu, tinogonesa kuita kwakawanda, nekukurumidza, uye kwemhando yepamusoro kusefa maitiro.

Chii chinosiyanisa midziyo yedu ndeye 100% automation kugona. Kuburikidza nekushandiswa kweakaomesesa proportional mavharuvhu, masisitimu edu anowana kudzora zvine hungwaru kusiyana kwekumanikidzwa, transmembrane pressure, uye kuyerera kwehuwandu. Level iyi ye automation haingokwidzi kushanda uye iko kurongeka kwesefa asi zvakare inoderedza zvakanyanya kukosha kwekutarisa nemanyorero, ichipa masisitimu edu akavimbika uye ane hushamwari mushandisi.

Tauya kuzokubatsira

Bata General

Kumbira Datasheet

Bata General