Chikumi 20, 2024

Chii chinonzi Regenerative Medicine? Ramangwana Reutano

Regenerative mushonga ibazi remushonga rinotarisa pakugadzirisa, kutsiva kana kuvandudza masero akakuvadzwa, matishu uye nhengo. Iyi nzira ine chinangwa chekugadzirisa zvese zviratidzo uye midzi inokonzeresa yehurwere nekugadzirisa chimiro uye basa rematishu akakuvadzwa. Kuvandudza matishu uye nhengo zvino zvinogona kurapa zvirwere zvakawanda nenzira dzatisina kumbobvira tafunga kuti dzinobvira.

Pamusoro pekugadzirisa zviripo pathologies, regenerative mushonga uri kutsvaga nzira dzekusimbisa uye kumutsiridza matishu kusati kwanyanya kukuvara. Iyi nzira yehutano inogona kubatsira kudzivirira zvimwe zvirwere, kuvandudza hutano hwese uye hutano nekudzikisa zvisingaperi uye kuderera kwemamiriro ezvinhu.

Inogona kurapa zvirwere zvisingarapike

Regenerative mushonga une chivimbiso chezvirwere izvo parizvino zvakaoma kurapa, senge mamwe cancer, Parkinson's, Alzheimer's, uye isingaperi moyo mamiriro. Pamusoro pezvo, mushonga wekuvandudza unogona kupa mhinduro dzekukuvara kwakanyanya, kupisa kwakanyanya, uye kugadzirisa matishu mukati autozvirwere zvekudzivirira zvirwere. Iko kugona kugadzira matishu matsva ane hutano kunopa mikana yekuvandudza hupenyu hwevarwere nekuvabatsira kuti vadzore mabasa akarasika nechirwere kana kukuvara.

Pamusoro pe, regenerative mushonga unogona kuderedza kudiwa kwevanopa nhengo dzemuviri, izvo zvishoma uye zvinowanzoda kuti varwere vamire kwenguva refu. Nekukwanisa kudzoreredza matishu uye nhengo murabhoritari, kudiwa kunogona kuzadzikiswa uye matambudziko ekurambwa kwenhengo akadzivirirwa.

Tsvagiridzo nebudiriro mundima iyi iri kufambira mberi nekukurumidza. Izvi zvinokonzerwa nekufambira mberi mubiotechnology, tishu engineering uye kunzwisisa kwemaitiro ekuvandudza padanho rema molecular uye cellular. Nekufambira mberi kwese uku, mushonga wekuvandudza unovimbisa kushandura hutano hwehutano, kupa tariro itsva kune varwere uye kushandura maitiro ekurapa munguva pfupi iri kutevera.

Nzvimbo huru dzemishonga yekuvandudza

  • Kurapa neserura: Aya anoshandisa stem maseru uye mamwe marudzi emaseru kuti agadzirise matishu akakuvadzwa. Mishonga iyi iri kugadzirwa kurapa mamiriro akasiyana-siyana, kubva pakukuvara kwemusana kusvika kuchirwere chemoyo. Stem cell, kunyanya, inokwanisa kusiyanisa mumhando dzakasiyana dzemasero, zvichiita kuti dzive dzakanyanya kushandiswa pakurapa kwekuvandudza.
  • Tissue mainjiniya: Nzvimbo iyi inosanganisa maseru, nzira dzeinjiniya uye zvinhu zvakakodzera kugadzira matishu anoshanda. Semuenzaniso, masero anogona kugadzirwa kuti aumbe matishu anogona kushandiswa mukusimukira. Iyi nzira inonyanya kuvimbisa pakusikwa kwenhengo dzekugadzira dzinogona kutsiva dzakakuvadzwa.
  • Gene-based regenerative mushonga: Izvi zvinosanganisira kushandiswa kwemaitiro ekurapa majini kugadzirisa kukanganisa kwemajini uye kukurudzira kuvandudzwa kwetishu. Advanced matekinoroji akadai CRISPR-Cas9 bvumira kunyatsogadzirisa majini, ichipa mhinduro dzinogona kuitika dzezvirwere zvemajini uye zvisingaperi.

Kufambira mberi mukugadzirisa gene

Gene therapy inogona kugadzirisa zvakananga shanduko muDNA yemurwere, ichipa mhinduro yakasimba yezvirwere zvakawanda zvemajini. Semuenzaniso, muzvirwere zvakagarwa nhaka senge cystic fibrosis, kugadzirisa shanduko inokonzeresa kunogona kudzoreredza basa rakajairwa kumasero akakanganisika. Uye zvakare, gene therapy inogona kushandiswa kugadzirisa immune system maseru, ichiita kuti ishande mukurwisa cancer nezvimwe zvirwere.

Nekune rimwe divi, mushonga wekuita gene-based regenerative uri kufambira mberi nekuda kwekugadzirisa magene, izvo zviri kuvhura mikana mitsva. Nekugadzirisa genetic mutations zvakananga mumasero omurwere, chisakiso chezvirwere zvakawanda, panzvimbo pezviratidzo zvadzo chete, chinogona kurapwa. Mumwe muenzaniso weiyo gene-editing tekinoroji ndeye CRISPR-Cas9, iyo inobvumira shanduko chaidzo kuti dziitwe kuDNA kugadzirisa kushanduka kwemajini kunokonzera zvirwere zvakakomba.

Gene therapies iri kushandiswa kugadzirisa immune system maseru kuti aite kuti anyatso kurwisa cancer nezvimwe zvirwere. Kufambira mberi mukuunza gene, kugadzirisa majini uye kuchengetedzeka kuri kuunza gene-based regenerative mushonga pedyo neicho chaicho.

TECNIC's role mu regenerative mushonga

TECNIC yakazvipira kutsigira kufambira mberi kwemishonga yekuvandudza nekupa mhinduro dzepamusoro dzebiotechnological. Yedu yezvigadzirwa, kubva kubioreactors kuenda kuTangential Flow Filtration masisitimu, yakagadzirirwa kutsigira nhanho imwe neimwe yekutsvagisa nekusimudzira maitiro.

  • Bioreactors: Nyatsodzora sero tsika nharaunda kuti ifambise kukura uye kusiyanisa kwema stem maseru. Isu tinogadzira mabioreactors edu kukwidziridza mamiriro etsika, izvo zvakakosha pakugadzira anoshanda maseru kurapwa.
  • Tangential Flow Filtration: Isu tinopa zvigadziriso zvekusefa kuchengetedza kuchena uye kunaka kwezvigadzirwa zvebiotech zvekushandisa pakurapa. TFF masisitimu akakosha pakuita zvinodhaka uye regenerative marapirwo akachengeteka uye anoshanda.
  • Bioprocess Supplies: Isu tinopa huwandu hwakasiyana hwezvishandiso izvo zvinogonesa kunyatsoita uye kushanda zvakanaka mumarabhoritari uye zvigadzirwa zvekugadzira. Zvigadzirwa zvedu, kubva kutsika midhiya kuenda kune reagents, zvakagadzirirwa vaongorori mune regenerative mushonga kuti vashandise.

Kugona kwemishonga yekudzorera kwakakura. At TECNIC, tinodada kuva chikamu cheshanduko iyi. Isu tinobatsira nharaunda yesainzi uye yekutanga-up kuti ivandudze. At TECNIC isu takazvipira kutyaira iyi inovimbisa ndima kumberi, kutsigira nharaunda yesainzi uye yekutanga kukurumidza kufambira mberi uye kuunza mabudiro kuvarwere nekukurumidza.

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Kuuya manje manje 

Tiri kupedzisa mashoko emidziyo yedu mitsva. Munguva pfupi, tichazivisa zvese zvinogadziridzwa. Kana iwe uchida kugamuchira zvese zvichangoburwa nezve zvigadzirwa zvedu, nyorera kune yedu tsamba yenhau kana kutevedzera yedu social media chiteshi. 

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gara informed nezve zvigadzirwa zvedu zvitsva, maitiro akanakisa, zviitiko zvinonakidza uye zvimwe zvakawanda! Mushure mekusaina kutsamba yedu, unogona kuzvibvisa chero nguva.

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Rushton denga

The Rushton impeller, inozivikanwawo se flat disk impeller. Yakabuda semhinduro kune matambudziko ekusanganisa uye oxygenation muindasitiri yebiotechnology. Dhizaini yayo yehunyanzvi yakakurumidza kuzivikanwa nekuda kwekugona kwayo kuburitsa kutenderera kuyerera, zvichiita kuti ive chiyero muchikamu kwemakumi emakore.

Unique Design
Zvishandiso muBiotechnology
Zvakanakira Kubudirira
Kugara uye Kuvimbika
Optimization for TECNIC

Pitch blade denga

Ichi chikamu chakakosha pakugadzirisa kusanganisa uye kuendesa hukuru mumasero tsika maitiro. Yayo chaiyo dhizaini inogonesa kugovaniswa kwezvinovaka muviri uye magasi, zvakakosha pakuchengetedza sero kushanda uye kukura pasi pemamiriro akanyanya.

Unique Design
Zvishandiso muBiotechnology
Zvakanakira Kubudirira
Kugara uye Kuvimbika

Rushton denga

Inoratidzwa neayo radial blades akaiswa perpendicularly kune shaft, iyo Rushton impeller inogadzirwa kuti ipe yakakwirira shear mazinga uye yakanakisa gasi kupararira, iyo inonyanya kushanda mumicrobial. Mune biotechnological application inosanganisira mabhakitiriya uye mbiriso, iyo Rushton impeller inokunda nekuita kuti homogeneous kusanganiswa uye kugovera gasi kwakaringana, kunyangwe mutsika dzakasimba.

Unique Design
Zvishandiso muBiotechnology
Zvakanakira Kubudirira
Kugara uye Kuvimbika

Cassette

Isu tinonzwisisa kukosha kwekushanduka uye kushanda zvakanaka mumarabhoritari maitiro. Ndicho chikonzero midziyo yedu yakagadzirirwa kuti ienderane nayo Cassette Filters, mhinduro yepamusoro yezvakasiyana-siyana zvefiltration application. Kunyangwe isu tisingagadziri mafirita zvakananga, masisitimu edu anogadziridzwa kuti atore mukana wakazara wemabhenefiti ayo Cassette mafirita anopa.

Cassette mafirita anozivikanwa nekukwira kwawo kwesefa uye kugona mukuparadzanisa, achiaita akanakira Ultrafiltration, microfiltration, uye nanofiltration application. Nekubatanidza mafirita aya mumidziyo yedu, tinofambisa maitiro anokurumidza uye anoshanda, tichiona mhedzisiro yemhando yepamusoro.

Midziyo yedu, kuenderana nayo Cassette mafirita, inopa hukuru hwekusiyana-siyana uye kuchinjika. Izvi zvinoreva kuti iwe unogona kusarudza sefa inonyatso kuenderana nezvido zvako, kuve nechokwadi chekuti kuyedza kwega kwega kana maitiro ekugadzira anoitwa nekunyatsogona uye nemazvo.

Uyezve, midziyo yedu inomira kunze kwayo 100% automation kugona. Tichishandisa advanced proportional mavharuvhu, isu nechokwadi chaiyo kudzora pamusoro kusiyana kwekumanikidzwa, transmembrane pressure, uye kuyerera kwehuwandu. ichi automation haingowedzere kushanda uye kurongeka kwekusefa asi zvakare inoderedza zvakanyanya kupindira kwemanyorero, zvichiita kuti masisitimu edu avimbike zvakanyanya uye mushandisi-ane hushamwari.

Hollow Fiber

Isu tinocherekedza basa rakakosha rekuchinjika uye kugona mumarabhoritari maitiro. Ndicho chikonzero midziyo yedu yakagadzirwa zvine hungwaru kuti ienderane nayo Hollow Fiber Filters, ichipa mhinduro yepamusoro kune yakafara spectrum yekusefa maapplication. Kunyange isu tisingagadziri masefa aya zvakanangana, masisitimu edu akakwenenzverwa kuti ashandise kugona kwakazara kwe Hollow Fiber filters.

Hollow Fiber mafirita anozivikanwa nekuita kwawo kwakasarudzika maererano nekusefa kwakanaka uye kugona. Iwo anonyanya kushanda kune maapplication anoda kubatwa zvinyoro nyoro kwemasamples, senge musero tsika uye sensitive biomolecular process. Nekubatanidza mafirita aya nemidziyo yedu, tinogonesa kuita kwakawanda, nekukurumidza, uye kwemhando yepamusoro kusefa maitiro.

Chii chinosiyanisa midziyo yedu ndeye 100% automation kugona. Kuburikidza nekushandiswa kweakaomesesa proportional mavharuvhu, masisitimu edu anowana kudzora zvine hungwaru kusiyana kwekumanikidzwa, transmembrane pressure, uye kuyerera kwehuwandu. Level iyi ye automation haingokwidzi kushanda uye iko kurongeka kwesefa asi zvakare inoderedza zvakanyanya kukosha kwekutarisa nemanyorero, ichipa masisitimu edu akavimbika uye ane hushamwari mushandisi.

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